Chemistry

We would like you to reflect on the material presented over the entire quarter and think about how the information has/can inform your own personal health as well as your career direction. Has anything changed since the midterm reflection? If so, please explain. Regardless of whether or not you are planning on pursuing a career related to healthcare, your reflection should discuss a minimum of three topics from class and how each topic broadened your understanding of pharmaceuticals, health care, and the role of the pharmacist in the community you live in.  You should also discuss how you will use this information in your day-to-day life and to what extent the information discussed so far has impacted your thoughts about your career.  For more information on Pharmacy Reflection read this: https://en.wikipedia.org/wiki/International_Pharmaceutical_Students%27_Federation#Pharmacy_Education_%28PE%29

Homework Case: Detected increase in incidence of rust afflicting either or both the vehicles produced by our automotive brand name. Said increase is defined as that which occurs before the guarantee period against rust expires, but also the period shortly after the expiry of the guarantee date. The term “shortly after” is given an arbitrary value of 18 months. Solution pathway:  1- You need to name your result or effect, the fish head, correctly. 2- Consider using the manufacturing categories (Slide 16) in Ishikawa Diagrams as a start. You may also choose your own categories if applicable, or you can augment the manufacturing categories with your own categories. 3- You determine your own categories as a result of affinity analysis and brainstorming sessions (Slides 18-20). 4- Come up with the possible categories for causes. Be careful when naming your causes, always making them measurable and non-descriptive. (Slides 22, 23) 5- See where the use of another tool like a statistical graph or chart can be useful. (Slide 24) 6- For at least one of the causes develop it into a new fishbone diagram. (Slides 33, 34) For more information on Rust  read this: https://en.wikipedia.org/wiki/Rust

Lab 13, Experiment 12. Titration of Hydrogen Peroxide Lab manual pages: 109-118 Pre-lab questions: page 111 – 112 Post-lab questions: 117 – 118 https://www.youtube.com/watch?v=ag2JGq5Omzo https://youtu.be/ag2JGq5Omzo https://youtu.be/Irs0-YrE7mA For more information on Hydrogen Peroxide read this: https://en.wikipedia.org/wiki/Hydrogen_Peroxide

Choose the topic for your course project.Familiarize yourself with PowerPoint with Audio Narration, which you will be using for your final presentation.Upload a “mini-presentation” introducing the molecule of your choice and explaining why you chose this topic for the course project.

Part I: pH change of an unbuffered solution 1.Load http://chemcollective.org/vlab/1022.Add a 250 mL beaker to your workspacefrom the stockroom.3.Add 10 mL of the protein solution.  (To add something to a beaker drag the solution on top of it until the prompt appears.)Then add 90 ml of water to the solution.Record the pH:_____________________(you find the pH by clicking on the beaker)4.To the same beaker under strong acids add 10 mL  0.10 M HClfrom the stockroom strong acid solutions. Record the pH: _____________________ (you find the pH by clicking on the beaker)5.What is the change in pH?_______________________________Part II: pH change of a buffered solution1.You have available the following:100.0mL of 1.0 MH2CO3 (weak acid; pKa= 6.4)100.0mL of 1.0 MNaHCO3(conjugatebase of H2CO3; but also a weak acidpKa=10.3)100.0 mL of Grey Goose Vodka100.0mL of 1.0 MNa2CO3(conjugate base of HCO3-)First, explain whichof the solutions aboveyou would useto make a 1 M Carbonate buffer at pH=6.0Next describe how much of each solution you would useto make a 1 M Carbonate buffer at pH=6.0and indicate the total volume.  Show any calculations2.Reload the Virtual lab page and create your buffer solution above.  Was your math correct? Record the pH:______________________ Acceptable ranges are +/-0.05 pH units3.Add another beaker to your workspace and add 10 mL of the protein solution. Then add 90 ml of buffer to the solution.Record the pH___________________4.To the same beaker add 10 mL  0.10 M HClfrom the stockroom strong acid solutions. Record the pH: _____________________ (you find the pH by clicking on the beaker)5.What is the change in pH?_______________________________Post lab questions1.In Part II, if instead of making a 1.00M carbonate solution, you made 0.100 M carbonate solution, how would this effect the change in pHwhen you added 0.1 M HCl to the protein buffer solution? What would be the new pH?  Show your calculations and also use the program. Compare the two results.2.If you wanted to make a buffer at pH=8.  Would carbonate be a suitable buffer?  Please explain why or why not?3.Why is it important thatbiochemistry solutions are in buffered solutions?

This week you will be in a discussion group of three students. Each student will explain and teach others how to solve one of the three problems below.  All three problems must be answered; decide among yourselves who will answer each question. You may present your lesson by typing your answer (although typing equations can be difficult), writing on a piece of paper then submitting a photo, or videotaping yourself (please provide a link to your video because it is advised not to upload large files to Canvas). Feel free to ask each other for help. You are also required to comment on both of your group members’ posts The diameter of the insulin molecule is about 2.70 nm. Convert this length to centimeters. A Prius has a gas mileage of 53 miles/gallon. How much will it cost to drive to Mammoth Lakes (547 km) when gasoline costs $3.11/gallon? How much will it cost to paint the walls of a room with the following dimensions: h=8.0 ft, l=20.0 ft, and w=15.0 ft? Approximately 172 square feet will require 1 gallon of paint. The paint you selected is $25.00 per gallon. (Ignore the space occupied by doors and windows)

Do the analysis of penicillin and beta-hemolytic strep. Describe the disease and also complications symptoms of disease beta-hemolytic strep. How it can be treated with the medication of penicillin or another way can be treated.“

 Lecture Question: Is BH3 polar or nonpolar? 

Need to write a 300-word report about the structure and biochemistry of the stratum corneum and relate it to the function of the barrier. There is no introduction and conclusion included in this writing so you crucially need to get straight to the point and be concise as it is only limited to 300 words. I have also attached a file on the marking criteria you need to follow to aim for good grades. As you can see, the first and second ‘content and ideas’ rubric is crucial to follow as it is worth at least 30 points.  There are two main parts to this writing: – Comprehensively outline the structure and show a sophisticated understanding of the biochemistry of the stratum corneum and explain why this is a good barrier (always relate everything you are saying to the barrier function). (This part is 60% of what is explained in this writing, so focus more on this more than the other which is written below). – Explain how the skin treatment ‘crystal microdermabrasion’ disrupts/impairs the barrier and how it recovers following this procedure. (again, do not write anything about the procedure process, get straight to the point). (Could be a couple of sentences or a very small paragraph). Everything explained has to be related back to the function of the barrier (if it doesn’t, then don’t include it in this writing). Relate at all times. Everything said needs to be explained in-depth and in detail. (Why and how) But as scientifically as possible, do not put unnecessary words as you need to think about the word count.   in regards to the marking criteria rubric, do not worry too much about the ‘referencing’ and ‘presentation’. Do not use images. and you need at least 15-20 references from peer-reviewed journal articles. No less than 15. They need to be relevant; the peer-reviewed journal articles have to be no less than 5 years old. Because I attend an Australian school, those are the rules of good research. Good research is needed!! As this is 300 words, 25 words more than the general order requirement, I will pay extra once completed and if this is outstanding quality, I will give a good tip.

Explain the importance of the biological buffer systems and gas relationships in our bodies.   Background This week we will study solids, liquids, gases, and acids and bases. The gas laws play an important role in respiratory care. Titrations are important in medicine as pharmacists and anesthesiologists, to name a couple of examples, use this method to determine the amount of medicine a patient needs. A healthy individual’s fluids must maintain a certain pH in order to function properly.   Prompt Choose one of these topics (gas laws, titrations, pH levels) and provide an example of how they are used in medicine. Discuss the importance of these principles in the treatment of a patient. Some examples are carbon dioxide playing a role in maintaining pH, the kidney’s role in helping to maintain blood pH, altitude sickness, how gas laws play a part in syringes and injections and determining medication dosage through titration, to name just a few.