Carefully read the attached article and answer the questions below Identify and discuss the following: what is known/not known about the topic and the gap in knowledge the study is intended to fill. the research design, purpose of the study, and setting.information about the sample: method;size;inclusion/exclusion criteria,attrition/loss to follow up/response rate, if any important characteristics of the sample. Appraise and debate the sampling methods. Consider the following questions:Was the sampling method and inclusion/exclusion criteria adequate to reduce sampling bias?Do the sample characteristics representative of the target population?Was the sample size adequate?Was there a decrease in sample size? If so, did the researchers identify decreases early and attempt to reduce the impact? Was a decrease, if any, adequately explained by the researchers?How would you rate the quality of the sampling procedures and your confidence in drawing inferences to the target population?