[Get Solution] Principles and Practice of Toxicology

Please don’t copy past anything from the internet, and citation should be rightBook: Richards, I. S.,&Bourgeois,M.M. (2014). Principles and practice of toxicology in public health (2nd ed.). Jones&BartlettLearning.https://online.vitalsource.com/#/books/9781284066197For theonlineBOOK:https://online.vitalsource.comusername: [email protected]: shehadeH3!CSU OnlineLibrary:http://libguides.columbiasouthern.edu/historyUsername:ahmed.shehadeh1Password:shehadeH3Citation Guide: please look in page6ofthislinkhttps://www.columbiasouthern.edu/downloads/pdf/success/citation-guideUnit VI IntroHello my fellow learners. Each week I try to come up with something clever and uplifting to say. I don’t want to waste your time with these announcements. If we were in a classroom setting I could dazzle you with witty and pithy comments. But online I can’t so I have to try and say something that you might just find useful. What I consistently see in your assessments and papers are simple mistakes according to APA guidelines. I know these guidelines are nit-picky and I also know that there is so much variability between professors that you don’t know what to expect. I know that is beyond frustrating, it was for me as well. But for me I want you to follow these guidelines. Is it that important to follow the instructions? I have one student now who was a bomb disposal guy. How important do you think it is to follow the instructions when defusing a bomb? So the instructions say to cut the green wire before cutting the yellow wire. Does it really matter? What is the worst that could happen? Can you all say “boom”. What if you were to receive a score of 100% for an assignment but I wasn’t paying attention to the detail and gave you 10% instead? It is only one more 0. What’s the big deal? Each assignment requires the use of references, in-text citations, word counts, and content. Some of you get it, some of you don’t, and some it seems just don’t care. I want you to succeed and graduate and come out here and help us save lives. That is how important this stuff is. We are not dealing with HR issues, or accounting issues, or logistics. We are SAFETY!! We watch our people and protect them from making fatal mistakes. One of our students is a firefighter out in Fresno, CA. You may have seen his video of him falling thru the roof of a fully involved garage fire. Do you think the little things made a difference to him that day? A couple of weeks ago on a wind turbine construction job in NE, a crane operator was killed when his rough terrain crane rolled over because of a soft roadway. He was crushed by the machine as it rolled over. I don’t know all the details, but it seems to me he didn’t have his seat belt on. Had he stayed in the cab he would have been protected and would be alive today? A little thing like a seat belt. Attention to detail makes or breaks us all. In SAFETY there is very little gray area; mostly it is black or white. It is either right or wrong. Is it safe or not? Is it right or not? Those are the questions that are asked everyday of us in safety. Please pay attention to the details because paying attention here might mean you will be paying attention out there and perhaps saving someone’s father or brother. Thank you.This unit deals with toxicity testing. NIOSH stuff. How much of what and how long can we deal with it? LD50 and LC50. Sound familiar? Hexavalent Chromium? Methyl ethyl ketone? How about ammonia and bleach? Ring any alarm bells?Unit VI Case Study· Weight: 12% of course grade· Grading Rubric· Due: Tuesday, 08/10/2020 11:59 PM (CST)InstructionsRecent studies support the potential of a drug that is derived from the metal iridium to effectively treat cancer. This experimental drug, Drug ZL105, has not been tested for efficacy and toxicity. Imagine that you are the one responsible for approving or denying the use of this drug within the United States. Your job is to propose the testing that is needed for this drug to be determined as safe and effective for the treatment of cancer in humans. In your research and discussion, you should address the questions below.1. What model(s) will you use for testing (i.e., animal, cell cultures, and computer simulations)? Explain the choice of model, and provide support for the reliability of the model. Discuss the pros and cons of your choice.2. In determining the safety and effectiveness of the drug, would it be necessary to test efficacy, toxicity, and lethality? Explain what each of these tests are for and whether or not one or more of the tests are necessary for your determination.3. Provide your thoughts on what information you hope to gather from your tests and whether or not the same protocol should be used for various categories of products such as drugs, cosmetics, and herbal medicines.Your case study assignment should be three to four pages in length and utilize at least three reliable references. Use APA style guidelines in writing this assignment, following APA rules for formatting, quoting, paraphrasing, citing, and referencing.ResourcesThe following resource(s) may help you with this assignment.§ Citation Guide