Carbonic Anhydrase

NOT THE WHOLE PAPER REQUIR LOOK ONLY FOR THE ATTACHED PART AND DO IT WITH ALL ITS REQUIREMENTS AND ZERO PLARIGZIME. The step will be included in uploaded files to have an idea about topic I in need to wrote about part that l will be uploading with all requirements and instructions below. 6) General Structural Features of the Enzyme: (if you cannot find all of the information for human enzyme, it is OK to describe from other organisms) ? Size of the protein. ? Primary structure = amino acid sequence ? Secondary structures such as alpha helices and beta sheets info ? Special features such as active site information, binding site, cofactor or prosthetic groups binding sites, or any other special features from tertiary structure and folding ? Quaternary structure (if it is monomer, dimer, trimer, or tetramer, in different organisms) and any other structural details you find for each subunit ? Is there any “homology” (= similarities) described for different organisms ? Any post-translational modification the protein undergoes ? Information from crystal structure studies by authors ? Now find references and find the pictures of the enzyme structure. Include them in the report, continue to give figure numbers, description (legend) and reference. 7) Physiological/Biological Function of the Enzyme: • Describe the general function of the enzyme = in which metabolic pathways the reaction catalyzed by the enzyme involved, or what roles does it play in the organisms = How is it useful for the organism • Make sure you have read the publications about this, not just what the database directly gives and include all the additional information you found from these publications. 8) Inhibitors (and activators if available): (you can find this in Brenda site and for details read the publications listed in the Brenda site) • Which are the inhibitors (and also activators) for your enzyme? (You can first get it from the Brenda site, and then look for details from the references the site lists). List all the ones you find. • Are these activators and inhibitors physiologically generated within the organism, or are they external ones? • What is the mechanism by which they activate or inhibit? (for at least one inhibitor and one activator you must describe in detail) • For the inhibitors (at least one inhibitor) what are the kinetics data (Ki Inhibitor constant, IC50 = What is the conc for 50% inhibition). • What are the consequences of inhibition or activation. 9) Medical, diagnostic, or industrial or other types of applications: Describe any of these applications you find from the databases and the references that are listed in the database, to find enough information. Which applications Why or how is the enzyme involved in these applications. 10) Mutations or other impairments, and Diseases caused by mutations, impairments or deficiencies of the enzyme: • What types of mutations or impairments or why the deficiencies are caused • What happens to the enzyme due to the above • What are the consequences? 11) Conclusions: (just create this title; you will work on the writing part for final step of the project) 12) Acknowledgements: (just create this title, but you will work on this for next step of the project) 13) References: In APA style, for ONLY those references you used this time, for the different sections of the report. Follow all instructions needed and zero plarigzime please.

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Sport Facilitator

Elaborate on being a youth sport’s facilitator. Why does this job interest you? What is attractive about this job? Talk about how you like working with kids and how this job would be rewarding.

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Printmaking Activity

In this Discussion Board Reflection, you will be connecting with your classmates about the low-tech, whatever-you-have-on-hand experimental Printmaking activity. The purpose of this forum is to “talk” about the experience with your classmates.  1.  Your Post Think about what you have learned so far about the nature of art, and the purposes that art serves, then jump in and share some thoughts about the activity and your approach to creating an experimental painting. Here are some prompts to start the discussion: What was it like to do the activity?   What was your idea?  What method did you use to make your print(s)?  What materials did you use?  Did you create an image that was realistic, abstract, or nonrepresentational?  Were you most intersted in conveying thoughts?  Feelings?  What the eye sees?  How did pattern and rhythm come into your composition?  Did this activity add to your understanding of the book chapters and/or of the other Lesson content?

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Diasporic Cultures

Need to do examples of 2 diasporic cultures in south Africa, explain what globalization is and also

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Protecting Pornography

Research question: Can pornography be protected as ‘speech’ and what types of regulations of pornography can be endorsed?You have to use external academic literature as well for writing this paper. There are many academic articles and books on google scholar about this topic.”Student should write a final paper of about 4000 words (with 10% margin). The student should read approximately 200-300 pages of additional literature for the paper.”Evaluation based on:(a) structure, style, language(b) the originality of the leading question and arguments(c) the ability of the student to consistently research a qeustion and develop an argument(d) the degree to which the student displays knowledge and insight related to the course’s readings and themesI have also attached comments doc of the advisor for this paper.

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 Environmental Health

Environmental justice ensures that all communities are treated fairly and are meaningfully involved in environmental-based decisions, such as where to build a new sanitary landfill, hazardous waste repository, industrial plant, or any other such site that could create an environmental hazard for those who live in the area.Describe a time when environmental injustice occurred. This can include any current or past events where the community was not fairly and meaningfully involved in the decision-making process.Who is or was negatively affected? What negative health effects could or did the community experience? What other social factors compound the negative health outcomes of the community?

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Professional Sports

I need research notes done BEFORE I submit a research essay on the same topic. this assignment is to have 6 academic sources( one per page) and have similar write ups to the attached example I give. single spaced- please follow the “ research notes example” I upload, and do my assignment with the topic “ does watching professional sports benefit people? why or why not?

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The Philosophy of Plato

Write a 4-6 page essay-style answer to one of the following questions:Question I: Plato’s PhaedoWhat does Simmias mean when he compares the soul to a harmony or attunement? Why does this comparison present a problem for Socrates in the Phaedo? How does Socrates respond to Simmias’ challenge? Is Socrates’ response convincing, in your view? Explain.This assignment involves three tasks:Task 1Explain in detail Simmias’ conception of the soul as a harmony or attunement. What are the relevant similarities between a harmony and the soul, on this picture? How does Simmias’ comparison present a problem for Socrates in the Phaedo? In other words, why can’t Socrates simply accept Simmias’ comparison? Explain.Task 2In the Phaedo, Socrates gives four distinct reasons to doubt Simmias’ conception of the soul as a harmony or attunement. Discuss two of these reasons. Why does Socrates doubt that Simmias’ conception of the soul is apt? Your job here is to explain whatever two reasons you selected as thoroughly as you can.Task 3Finally, your job here is to focus on one of the reasons you discussed in Task 2, and to develop a response to it on Simmias’ behalf. Imagine that you are a participant in the dialogue. How would you come to Simmias’ defense, if you had to? For example, do you think that one of Socrates’ reasons relies on an error or a confusion of some kind? If so, then explain the error or confusion as thoroughly as you can.Question II: Plato’s Republic, Book 2In Book 2 of the Republic, Glaucon argues that everyone who practices justice does so “unwillingly” (358c). In your view, what does Glaucon mean by this? How does Glaucon support this part of his position? Reconstruct Glaucon’s case with numbered premises. Does his argument succeed, in your view? Explain. This assignment involves three tasks:Task 1First, interpret Glaucon’s thesis, explaining its key terms. In particular, what does Glaucon mean by “justice”? And what does he mean by the term “unwillingly”? Defend your interpretation with textual evidence. Task 2Begin by reconstructing the argument found at 359b-360d. Number your premises, stating them as clearly as you can. Make sure to list only those premises you take to be essential for generating the conclusion. The conclusion of the argument should also be clear in your reconstruction. Next, identify what support (if any) you find in the text for each of the premises. What reasons does Glaucon give on behalf of each of the premises in question? Where you find support for the premises to be lacking, provide whatever defence you can for the under-supported premise(s). For clarity’s sake, make sure to refer to the premises according to the numbering you supplied earlier in Task 2.Task 3Finally, you should evaluate Glaucon’s case. Is Glaucon’s argument persuasive, in your view? Do you think it relies on a dubious premise? If so, then identify the premise in question by the numbering you supplied in Task 2. For example, maybe you think Glaucon’s case relies on a questionable thought experiment. If so, then explain where you think the thought experiment goes wrong. On the other hand, maybe you think Glaucon’s argument is sound. If so, then you should develop what you take to be the strongest objection to Glaucon’s argument, and then explain why you think the objection fails. Question III: Plato’s Republic, Book 4According to Socrates in the Republic, how many parts does the soul have, and what are the natures of these parts? What is his method for proving that the soul has precisely this many parts? Develop what you take to be the strongest objection to Socrates’ division of the soul.This assignment involves three tasks:Task 1For Task 1, explain Socrates’ conception of the soul and its parts. What distinguishes each of the soul’s parts? What human motivations do the soul’s parts represent, respectively? Your job here is to outline the model of the soul that Socrates will go on to generate.Task 2Explain Socrates’ method for dividing the soul into parts. To what general principle does Socrates appeal in justifying this method? Next, explain how Socrates applies this method so as to generate the division of soul you outlined in Task 1. What specific cases does Socrates use to prove that the putative parts of soul are in fact distinct?Task 3Develop what you take to be the strongest objection to Socrates’ division of soul. Be sure to make clear the precise character of your objection. For example, do you object to Socrates’ method for dividing the soul (as you explained it in Task 2)? If so, explain as thoroughly as you can your reasons for rejecting this method. Alternatively, maybe you approve of Socrates’ method of division, but you also worry that he is misapplying this method when he divides the soul. If so, then explain as thoroughly as you can where you think Socrates is misapplying his method.Some Instructions:Assignments must be written in 12 pt. font and double-spaced, with one-inch margins and numbered pages. Make sure that your name and student number appear at the top of the first page. Title pages are not necessary.Your introductory paragraph must include a clear thesis statement. A thesis statement has two main components: i) A clear statement of the position you will take in the paper; and ii) a brief, clear outline of the case you will make in support of that position.Make sure to explain any technical terms you use. What constitutes a technical term? Ask yourself the following question: ‘Would a friend of mine who has never taken a philosophy course readily understand what the term means?’ If the answer is no, then it’s a technical term. Explain it.Use direct quotations (i.e. “____”) only on those rare occasions when you want to call attention to the author’s precise wording. Otherwise, explain the reading in your own words and cite accordingly in parentheses or footnotes.Any standard citation style (e.g. APA, MLA, Chicago) is acceptable, but please remain consistent in your paper. Make sure to give citations for Plato’s dialogues using Stephanus numbers (e.g. 434a; 435a-436b). If you have any questions about citations, ask the instructor. 

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Role Of Social Media

Write a research paper (minimum 6 pages including the Works Cited page) on the following topic using MLA documentation style.  Topic : Role of Social Media in Effective Communication and Collaboration The paper must contain at least one footnote and five references. You must cite the sources in the text of your paper using in-text (parenthetical) citations. Any source information provided in the text must correspond to the source information listed on the Works Cited page. Sources must be peer-reviewed journal articles

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Restorative Art

Question:  Is the “formaldehyde is evil and bad for the planet and people and therefore shouldn’t be used in embalming” argument valid?  Could one not posit that embalming with formaldehyde is an organic option since formaldehyde is organic?  Support your answers.Resources You may use your textbook, the recorded lecture, or any scholarly resource at your disposal. A scholarly source is a source that has been peer reviewed. A good resource for this is Google Scholar.Acceptable Length: The essay should be approximately 1000 words.

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