Bioinformatics And Genome

3. Lander and Waterman derived formulae for the expected completeness of an assembly as a function of coverage c = NL/G, where G = genome length, N = number of reads, L = read length. Then probability that a base is not sequenced = e-c total expected gap length = Ge-c total number of gaps = Ne-c (a) what fraction of a genome could you expect to assemble from eightfold coverage? Present your result as percentage. (b) What total gap length would you expect in an assembly of a 2 Mb target genome size from eightfold coverage? (c) How many gaps would you expect in an assembly of a 2 Mb target genome size from an eightfold coverage of fragments with a read length of 500? (d) You want to sequence to sequence a 4 Mb genome by the shotgun method, by assembling random fragments with read length 500. What coverage would you require, to expect no more than four gaps, assuming no complications arising from repetitive sequences or skewed base composition?

Struggling to find relevant content? Order a custom essay on
Bioinformatics And Genome
Let our experts save you the hassle
Order Now
Calculate the price
Make an order in advance and get the best price
Pages (550 words)
$0.00
*Price with a welcome 15% discount applied.
Pro tip: If you want to save more money and pay the lowest price, you need to set a more extended deadline.
We know how difficult it is to be a student these days. That's why our prices are one of the most affordable on the market, and there are no hidden fees.

Instead, we offer bonuses, discounts, and free services to make your experience outstanding.
Sign up, place your order, and leave the rest to our professional paper writers in less than 2 minutes.
step 1
Upload assignment instructions
Fill out the order form and provide paper details. You can even attach screenshots or add additional instructions later. If something is not clear or missing, the writer will contact you for clarification.
s
Get personalized services with GPA Fix
One writer for all your papers
You can select one writer for all your papers. This option enhances the consistency in the quality of your assignments. Select your preferred writer from the list of writers who have handledf your previous assignments
Same paper from different writers
Are you ordering the same assignment for a friend? You can get the same paper from different writers. The goal is to produce 100% unique and original papers
Copy of sources used
Our homework writers will provide you with copies of sources used on your request. Just add the option when plaing your order
What our partners say about us
We appreciate every review and are always looking for ways to grow. See what other students think about our do my paper service.
Technology
I can work with it and massage it to what I need. Thank You
Customer 452827, July 19th, 2022
Social Work and Human Services
Thank You, Don!!! :)
Customer 452587, November 9th, 2021
ENVIRONMENT SCIENCE
EXCELLENT
Customer 452813, June 19th, 2022
Other
GREAT
Customer 452813, June 25th, 2022
Social Work and Human Services
Great Work!
Customer 452587, August 31st, 2021
Other
AWESOME
Customer 452813, June 21st, 2022
Medicine
Thank you for the great services
Customer 452635, April 24th, 2022
Social Work and Human Services
Great Work!
Customer 452587, October 13th, 2021
Nursing
Fantastic work on this project as usual.
Customer 452707, July 5th, 2022
Other
Thank you for a well written paper!!!
Customer 452557, January 19th, 2022
Other
GOOD
Customer 452813, July 5th, 2022
Nursing
Thank you to the writer and also thank you to the support team I got an A for the paper
Customer 452635, June 17th, 2022
OUR GIFT TO YOU
15% OFF your first order
Use a coupon FIRST15 and enjoy expert help with any task at the most affordable price.
Claim my 15% OFF Order in Chat
error: Content is protected !!