Abnormal Electromyography

Myasthenia Gravis  Mandy VanBibber posted Dec 16, 2020 1:44 AM  Subscribe Previous   Next   This page automatically marks posts as read as you scroll. Adjust automatic marking as read setting A 30 year old female presents with muscle weakness and fatigue. Abnormal electromyography testing and a positive increase in ACTH receptor test is reported. Her final diagnosis is Myasthenia Gravis. Myasthenia gravis is a type of autoimmune disorder.  Antibodies are proteins made by the body’s immune system when it finds harmful substances.  Antibodies in this case is produce when the immune system mistakes healthy tissues to be a harmful substance.   In people with myasthenia gravis, the body produces antibodies that block the muscle cells from receiving the neurotransmitters from the nerve cells.  Myasthenia gravis can affect people at any age but is most common in young women and older men (Myasthenia gravis, 2019).   Describe the normal synaptic transmission at the Neuromuscular Junction (NMJ). Neuromuscular transmission depends on the blend, storage, and release of acetylcholine from the presynaptic motor nerve ending at the neuromuscular junction, binding of acetylcholine to nicotinic receptors on the postsynaptic region of the muscle cell membrane, with simultaneously generating of the action potential and rapid influx of acetylcholine by the acetylcholinesterase enzyme present in the synaptic cleft (Naguib, 2007).             2.  Why is the ACTH level increased? If adrenal glands are healthy and functioning normally, cortisol level will rise in response to ACTH you are given in the ACTH receptor test.  This test was done to rule out primary adrenal insufficiency (Montes-Villarreal, 2020)   Explain why the patient with myasthenia gravis cannot generate consistent action potentials in the muscle fiber.    Acetylcholine receptor antibodies bind to the acetylcholine receptors and block many of the receptors, so the action or activity of this acetylcholine neurotransmitter results in a reduced movement of the voluntary muscle (Myasthenia gravis, 2019).   Treatment for the patient involves pyridostigmine—what does this drug do and how would it benefit our patient? Pyridostigmine inhibits acetylcholinesterase in the synaptic cleft by competing with acetylcholine for attachment to acetylcholinesterase and slows down the hydrolysis of the acetylcholine effectively increasing the efficiency of the cholinergic transmission in the neuromuscular junction, prolonging the effects of acetylcholine (Apinyawasisuk, Chongpison, Thitisaksakul, & Jariyakosol,2020).   Reference Apinyawasisuk, S., Chongpison, Y., Thitisaksakul, C., & Jariyakosol, S. (2020). Factors Affecting Generalization of Ocular Myasthenia Gravis in Patients With Positive Acetylcholine Receptor Antibody. American Journal of Ophthalmology, 209, 10-17. http://dx.doi.org/10.1016/j.ajo.2019.09.019   Montes-Villarreal, J., Perez-Arredondo, L., Rodriguez-Gutierrez, R., Alejandro Diaz Gonzalez-Colmenero, Solis, R. C., González-González, J. G., & Mancillas-Adame, L. (2020). SERUM MORNING CORTISOL AS A SCREENING TEST FOR ADRENAL INSUFFICIENCY. Endocrine Practice, 26(1), 30-35. http://dx.doi.org/10.4158/EP-2019-0327   Myasthenia gravis (2019). Johns Creek: Ebix Inc. Retrieved from https://search.proquest.com/other-sources/myasthenia-gravis/docview/2085179337/se-2?accountid=100141 Naguib, M., W.B. Saunders, (2007). Complications in Anesthesia (Second Edition),Chapter 116 – Myasthenic Disorders, pages 448-449, (http://www.sciencedirect.com/science/article/pii/B9781416022152501216)

Struggling to find relevant content? Order a custom essay on
Abnormal Electromyography
Let our experts save you the hassle
Order Now
Calculate the price
Make an order in advance and get the best price
Pages (550 words)
$0.00
*Price with a welcome 15% discount applied.
Pro tip: If you want to save more money and pay the lowest price, you need to set a more extended deadline.
We know how difficult it is to be a student these days. That's why our prices are one of the most affordable on the market, and there are no hidden fees.

Instead, we offer bonuses, discounts, and free services to make your experience outstanding.
Sign up, place your order, and leave the rest to our professional paper writers in less than 2 minutes.
step 1
Upload assignment instructions
Fill out the order form and provide paper details. You can even attach screenshots or add additional instructions later. If something is not clear or missing, the writer will contact you for clarification.
s
Get personalized services with GPA Fix
One writer for all your papers
You can select one writer for all your papers. This option enhances the consistency in the quality of your assignments. Select your preferred writer from the list of writers who have handledf your previous assignments
Same paper from different writers
Are you ordering the same assignment for a friend? You can get the same paper from different writers. The goal is to produce 100% unique and original papers
Copy of sources used
Our homework writers will provide you with copies of sources used on your request. Just add the option when plaing your order
What our partners say about us
We appreciate every review and are always looking for ways to grow. See what other students think about our do my paper service.
Nursing
This is great! Thank you
Customer 452679, December 16th, 2021
Business and administrative studies
Thank you very much for your help.
Customer 452861, September 16th, 2022
Technology
My paper was sent back after my due date time
Customer 452901, November 12th, 2022
Nursing
Thank you so much. I didn't know where to start and you did an amazing job. Thanks and have a great night.
Customer 452925, March 16th, 2023
Political science
THANK YOU
Customer 453001, April 25th, 2024
Human Resources Management (HRM)
Perfect
Customer 452701, August 15th, 2023
Other
Great job
Customer 452813, July 27th, 2023
Nursing
Always a wonderful experience!
Customer 452453, February 23rd, 2023
Other
Excellent work, delivered ahead of schedule
Customer 452467, January 19th, 2024
Human Resources Management (HRM)
Thanks.
Customer 452701, August 1st, 2023
Social Work and Human Services
Excellent Work!
Customer 452587, July 28th, 2021
Human Resources Management (HRM)
Thanks for your support.
Customer 452701, April 24th, 2023
OUR GIFT TO YOU
15% OFF your first order
Use a coupon FIRST15 and enjoy expert help with any task at the most affordable price.
Claim my 15% OFF Order in Chat

Good News ! We now help with PROCTORED EXAM. Chat with a support agent for more information